Immune Modulation of Brown(ing) Adipose Tissue in Obesity
نویسندگان
چکیده
منابع مشابه
White adipose tissue browning and obesity
Obesity and metabolic disorders are major health concerns worldwide. Although a range of therapies have been developed, these pharmaceutical treatments often have adverse side effects or limited efficacy. Therefore, there is a growing need of novel therapeutics to prevent or treat obesity. Obesity is thought to be caused by an imbalance between energy intake and energy consumption. Increasing e...
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Obesity is a major risk factor for metabolic disease, with white adipose tissue (WAT) inflammation emerging as a key underlying pathology. Alongside its major role in energy storage, WAT is an important endocrine organ, producing many bioactive molecules, termed adipokines, which not only serve as regulators of systemic metabolism, but also possess immunoregulatory properties. Furthermore, WAT ...
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ژورنال
عنوان ژورنال: Endocrine Reviews
سال: 2016
ISSN: 0163-769X,1945-7189
DOI: 10.1210/er.2016-1066